Linkage Disequilibrium

2/05

2/19

HW 1

Required Readings:

Patterns of Linkage Disequilibrium in the Human Genome

Linkage Disequilibrium -- understanding the evolutionary past and mapping the medical future

tagSNP Selection

2/27

3/12

HW 2

Useful Links:

Linkage Disequilibrium: Models and Data

An utter refutation of the ‘Fundamental Theorem of the HapMap’

Selecting a Maximally Informative Set of Single-Nucleotide Polymorphisms for Association Analyses Using Linkage Disequilibrium

Optimal Haplotype Block-Free Selection of Tagging SNPs for Genome-Wide Association Studies

Conservative Extensions of Linkage Disequilibrium Measures from Pairwise to Multi-loci and Algorithms for Optimal Tagging SNP Selection

Haplotype Phasing

4/8

4/19

HW 3

clark.jar

em.jar

GWAS Simulation Presentation by Daniel