1. Look at Mendel's experiment #2 on page 17 of his paper (using the www.esp.org version). How did he know he had 16 Aabc and 78 AaBbCc forms? I.e. when he writes "...further investigation showed..." what did he mean? Be as specific as possible.
2. Suppose you have two inbred strains of rabbits. One strain is white with long ears, and the other is brown with short ears. You cross the two strains and get an F1, and then an F2. The F1 generation is all white with long ears.
b. If color and ear length are determined by two separate and unlinked Mendelian factors/characteristics, what will be the phenotypes and genotypes in the F2?
c. If color and ear length are determined by two separate Mendelian factors/characteristics that on the same pair of chromosomes, what will be the phenotypes and genotypes in the F2?
3. Describe Mendelian "independent assortment" and "random segregation" in terms of meiosis. What is the meaning of "gene" that this implies?
4. Start with Morgan's white-eyed male and a homozygous red-eyed female. How would you generate progeny that would be (in theory at least) 100% white-eyed? Include all the charts/diagrams/squares in your answer.
5. Using Sturtevant's paper, do the following:
b. Explain how Sturtevant defines the unit for measuring distance on the chromosome.
c. Diagram the crosses that gave the OP distance of 29.4 in Table 2 (see Table 8 for the data). Show in your diagrams the phenotypes and genotypes of the parents and progeny and indicate which progeny are the recombinant forms.
d. Suppose you wanted more data on the OP distance. You have pure-breeding flies that are black eosin, black vermillion, and black eosin-vermillion; but, you do not have any wild type flies. What are the best crosses to do?
6. In the second section of his 1923 essay, "THE BEARING OF MENDELISM ON THE ORIGIN OF SPECIES," Morgan writes of a notable advance in our understanding that genetics has provided since Darwin wrote. What is the advance and why does Morgan think it so significant?